VTE is a leading
cause of Death and
Disability Worldwide.

Yet, no one talks about it.

VTE is a Silent Killer

For 1 in 4 patients, a fatal PE is the first symptom of VTE.

Blood Clots are Deadly and a
Significant, Growing Public Health Problem

Affected by Blood Clots
Blod Clot Related Deaths
= 100, 000

Blood Clots affect as many as

900,000 Americans

each year leading to approximately

100,000 premature deaths


of blood clots are healthcare associated

Although there are many reasons a person might develop a blood clot, about half of them are directly related to a recent hospitalization or surgery and most of these do not occur until after discharge



of fatal VTE events occur in
acutely ill medical patients
Huang et al, 2015


1 in 4

people worldwide die of
VTE-related conditions
World Thrombosis Day

In the US, VTE is more deadly than colon cancer,
diabetes, flu, and pneumonia

VTE causes ~100,000 confirmed annual deaths in the United States alone.









The Unmet Medical Need

There is a need for extended-duration VTE prophylaxis that provides:

VTE risk reduction during the highest risk period

Significant risk reduction versus standard of care


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